PFUND Completes NIH Drug Screening

Following the screening of 1,040 specially selected FDA approved drugs in our experimental model system, the data was shared with the Consortium of 26 laboratories nationwide. This project, sponsored by The National Institutes of Health (NIH), the National Institute of Neurological Disorders and Stroke (NINDS), and the ALS Association, was a focused effort to fast-track new therapeutic strategies against ALS into the clinic. The data from all 26 research teams will be available to the public on the Internet in the form of a database containing all of the screening results. In addition, preliminary discussions of the data will be published in a letter to the journal Nature in the near future. In our own PFUND laboratory, the drug screen has produced exciting new insights into ALS disease. These leads form the basis for new research projects and grant proposals that are now underway in the lab.